Berman J W, Basch R S
Exp Hematol. 1983 Jan;11(1):43-55.
An antigen (MG-1) which behaves as a lineage marker for immature granulocytes and cells of the monocytic series in mice is described. It is identified by rabbit anti-mouse brain antiserum, which has been exhaustively absorbed with thymocytes, red blood cells, and a Thy-1 negative variant of a T-cell lymphoma. MG-1 is present on immature granulocytes, declines in its surface expression as the cells differentiate and is absent from the most mature cells (segmented) of the series. Early monocytes are strongly positive for MG-1 and, with maturity, the amount of cell surface antigen increases. Adherent, phagocytic macrophages are brilliantly positive when stained with anti-MG-1 antiserum in an immunofluorescence assay. The antigen is present on most of the adherent cells of the lung, spleen and peritoneum. Many multipotential stem cells also express low levels of this antigen as do some bone marrow B cells.
描述了一种抗原（MG-1），它可作为小鼠未成熟粒细胞和单核细胞系细胞的谱系标记物。它由兔抗小鼠脑抗血清识别，该抗血清已用胸腺细胞、红细胞和T细胞淋巴瘤的Thy-1阴性变体彻底吸收。MG-1存在于未成熟粒细胞上，随着细胞分化其表面表达下降，并且在该系列最成熟的细胞（分叶细胞）中不存在。早期单核细胞对MG-1呈强阳性，随着成熟，细胞表面抗原量增加。在免疫荧光试验中，贴壁吞噬巨噬细胞用抗MG-1抗血清染色时呈明亮阳性。该抗原存在于肺、脾和腹膜的大多数贴壁细胞上。许多多能干细胞也表达低水平的这种抗原，一些骨髓B细胞也是如此。
