Hawker P C, Givel J C, Keighley M R, Alexander-Williams J, Allan R N
Gut. 1983 Apr;24(4):284-7. doi: 10.1136/gut.24.4.284.
The outcome among 39 patients with enterocutaneous fistulae complicating Crohn's disease has been reviewed. The patients were considered in two groups: (1) no disease - all were early postoperative fistulae (n = 9); (2) active disease (i) without abscess formation (n = 16), (ii) with abscess formation (n = 14). Postoperative fistulae with no evidence of active Crohn's disease healed spontaneously. Fistulae in the presence of active disease did not heal even with prolonged medical management. The only effective treatment was excision of the diseased segment from which the fistulae arose and any distal obstruction. None of the fistulae closed surgically has recurred.
对39例克罗恩病并发肠皮肤瘘的患者的治疗结果进行了回顾。这些患者被分为两组:(1)无疾病——均为术后早期瘘(n = 9);(2)活动性疾病:(i)无脓肿形成(n = 16),(ii)有脓肿形成(n = 14)。无活动性克罗恩病证据的术后瘘可自愈。存在活动性疾病时的瘘即使经过长期药物治疗也不会愈合。唯一有效的治疗方法是切除产生瘘的病变节段及任何远端梗阻部位。手术闭合的瘘均未复发。