McIntyre P B, Ritchie J K, Hawley P R, Bartram C I, Lennard-Jones J E
Br J Surg. 1984 Apr;71(4):293-6. doi: 10.1002/bjs.1800710416.
The development of an enterocutaneous fistula has frequently been reported as being attended by a high morbidity and mortality, particularly in patients with inflammatory bowel disease who have high output, small bowel fistulas. We report a series of 114 patients who required treatment for 132 fistulas during the period 1976-1981. Fifty-one fistulas originated in the jejunum and ileum, and forty-eight patients had Crohn's disease. The majority of patients required surgical intervention and parenteral nutrition was required in forty-eight cases. Using an integrated programme of nursing, medical and surgical care, the overall healing rate was 90.9 per cent and the mortality 5.3 per cent. With the therapeutic methods currently available, an unacceptably high mortality rate in these patients can be avoided.
肠皮肤瘘的发生常常伴有高发病率和死亡率，尤其是在患有高流量小肠瘘的炎症性肠病患者中。我们报告了1976年至1981年期间需要治疗132例瘘管的114例患者。51例瘘管起源于空肠和回肠，48例患者患有克罗恩病。大多数患者需要手术干预，48例患者需要肠外营养。采用护理、内科和外科综合治疗方案，总愈合率为90.9%，死亡率为5.3%。采用目前可用的治疗方法，可以避免这些患者出现令人难以接受的高死亡率。
