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F'质粒对鼠疫耶尔森菌毒力的抑制作用

Repression of the virulence of Yersinia pestis by an F' plasmid.

作者信息

Zsigray R M, Lawton W D, Surgalla M J

出版信息

Infect Immun. 1983 Feb;39(2):974-6. doi: 10.1128/iai.39.2.974-976.1983.

DOI:10.1128/iai.39.2.974-976.1983
PMID:6832826
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC348043/
Abstract

An F-lac plasmid from Escherichia coli was transferred to virulent Yersinia pestis, resulting in the repression of virulence. The Y. pestis F-lac clones retained all of the known virulence traits but were avirulent and calcium independent. Every lac segregant derived from the F-lac clones was fully virulent and calcium dependent.

摘要

来自大肠杆菌的F - lac质粒被转移到有毒力的鼠疫耶尔森菌中，导致毒力受到抑制。鼠疫耶尔森菌F - lac克隆保留了所有已知的毒力特征，但无毒力且不依赖钙。从F - lac克隆衍生出的每个lac分离株都具有完全的毒力且依赖钙。

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本文引用的文献

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TRANSMISSION OF A RESISTANCE TRANSFER FACTOR FROM ESCHERICHIA COLI TO 2 SPECIES OF PASTEURELLA.抗药转移因子从大肠杆菌向两种巴斯德氏菌的传递
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Plasmid associated with pathogenicity and calcium dependency of Yersinia enterocolitica.与小肠结肠炎耶尔森菌致病性和钙依赖性相关的质粒
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Plasmid-mediated tissue invasiveness in Yersinia enterocolitica.小肠结肠炎耶尔森菌中质粒介导的组织侵袭性
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Essential virulence determinants of different Yersinia species are carried on a common plasmid.不同耶尔森氏菌属的关键毒力决定因素由一个共同的质粒携带。
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