Richardson J F
J Antimicrob Chemother. 1983 Feb;11(2):163-7. doi: 10.1093/jac/11.2.163.
Four hundred and forty-nine strains of staphylococci, 386 Staphylococcus epidermidis and 63 Staph. saprophyticus were tested by MIC and disc for susceptibility to trimethoprim. About 30% of clinically significant strains of Staph. epidermidis were resistant to trimethoprim; this fell to 12.6% in strains from normal flora. The frequency of resistance among clinically significant strains did not alter from 1976 to 1980. Strains of Staph. saprophyticus were uniformly sensitive to trimethoprim.
对449株葡萄球菌进行了甲氧苄啶敏感性的微量肉汤稀释法（MIC）和纸片法检测，其中包括386株表皮葡萄球菌和63株腐生葡萄球菌。约30%具有临床意义的表皮葡萄球菌菌株对甲氧苄啶耐药；而来自正常菌群的菌株中这一比例降至12.6%。1976年至1980年间，具有临床意义的菌株中的耐药频率没有变化。腐生葡萄球菌菌株对甲氧苄啶均敏感。
