慢性淋巴细胞增殖性疾病患者血清对中性粒细胞趋化性的损害。
Impairment of neutrophil chemotaxis by serum from patients with chronic lymphoproliferative disease.
作者信息
Jayaswal U, Roper S, Roath S
出版信息
J Clin Pathol. 1983 Apr;36(4):449-53. doi: 10.1136/jcp.36.4.449.
Abstract
The sera of 74 individuals with chronic lymphoproliferative disease were screened for the presence of inhibitory activity against neutrophil chemotaxis. This was present in more than half the patients with IgA myeloma and Hodgkin's disease but was less common in chronic lymphocytic leukaemia, lymphocytic lymphoma and non-IgA paraproteinaemia. Heating the sera prior to testing frequently enhanced inhibitory activity particularly in myeloma and lymphoma.
摘要
对74例慢性淋巴细胞增殖性疾病患者的血清进行检测，以筛查其中是否存在针对中性粒细胞趋化性的抑制活性。超过半数的IgA骨髓瘤和霍奇金病患者存在这种抑制活性，但在慢性淋巴细胞白血病、淋巴细胞淋巴瘤和非IgA副蛋白血症患者中则较少见。检测前对血清进行加热处理，常常会增强抑制活性，尤其是在骨髓瘤和淋巴瘤患者中。
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