半乳糖对离体大鼠脑毛细血管摄取己糖和氨基酸能力的影响

On the ability of galactose to influence hexose and amino acid uptake by isolated rat brain capillaries.

作者信息

Segal S, Hwang S M

出版信息

J Neurochem. 1983 May;40(5):1373-6. doi: 10.1111/j.1471-4159.1983.tb13579.x.

DOI:10.1111/j.1471-4159.1983.tb13579.x

Abstract

The uptake of glucose, 2-deoxyglucose, proline, methionine, and alpha-methylamino isobutyric acid was studied in brain capillaries preincubated with 50 mM galactose either in vitro or isolated from galactose-fed rats. The uptake was not decreased in both cases. The linear rate of glucose oxidation by capillaries was also not altered by preincubation with galactose.

摘要

在体外或从喂食半乳糖的大鼠分离的脑毛细血管中，研究了预先用50 mM半乳糖孵育的脑毛细血管对葡萄糖、2-脱氧葡萄糖、脯氨酸、蛋氨酸和α-甲基氨基异丁酸的摄取。在这两种情况下，摄取均未降低。毛细血管对葡萄糖的线性氧化速率也不会因用半乳糖预孵育而改变。