Klein G, Urbanek R, Köhler D, Matthys H
Klin Padiatr. 1983 Jan-Feb;195(1):33-7. doi: 10.1055/s-2008-1034037.
Examination of the lung function and bronchial provocation tests are useful for confirmation of an airway obstruction. There is a need for measurements independent of child cooperation. The standard method is body plethysmography. Forced oscillation method and interrupted occlusion method were recently introduced. Measurements of airway resistance by body plethysmography (Raw), by forced oscillation (Ros) and by interrupted occlusion method (Rvd) were compared during 78 inhalative bronchial provocation tests. The correlation index between Raw and Ros total was 0,84 and between Raw and Rvd 0,89. There is a good sensitivity and specifity in allergen bronchial provocation testing in all three methods. A bronchial sensitivity is confirmed in body plethysmography by 100% increase of Raw. In the interrupted method a 50% increase of Rvd in children smaller than 165 cm and in forced oscillation method a relative increase of 25% (0,15 kPa/l/s) is sufficient to assess a bronchial sensitivity to tested allergen.
肺功能检查和支气管激发试验有助于确诊气道阻塞。需要进行不依赖儿童配合的测量。标准方法是体容积描记法。最近引入了强迫振荡法和间断阻断法。在78次吸入性支气管激发试验中,比较了通过体容积描记法(Raw)、强迫振荡法(Ros)和间断阻断法(Rvd)测量的气道阻力。Raw与Ros总体之间的相关指数为0.84,Raw与Rvd之间的相关指数为0.89。三种方法在变应原支气管激发试验中均具有良好的敏感性和特异性。在体容积描记法中,Raw增加100%可确认支气管敏感性。在间断法中,身高小于165 cm的儿童Rvd增加50%,在强迫振荡法中相对增加25%(0.15 kPa/l/s)足以评估对受试变应原的支气管敏感性。