Donovan J C, Stokes W S, Montrey R D, Rozmiarek H
Lab Anim Sci. 1983 Feb;33(1):86-9.
Twenty of 47 recently imported cynomolgus monkeys (Macaca fascicularis) were found to have malarial infections. The agent identified was Plasmodium inui. All infections were subclinical in nature. Parasitemias ranged from 10 to 900 parasites/mm3 of whole blood. Pre- and post-treatment hematologic values were evaluated following treatment with chloroquine. Treatment was effective in clearing parasitemias from 13 of 14 infected monkeys. Pretreatment values of hematocrit, hemoglobin, and mean corpuscular volume were significantly different in infected animals compared to noninfected animals. While post-treatment hemoglobin and hematocrit values returned to noninfected control levels, mean corpuscular volume values of infected animals remained significantly lower in the post-treatment period.
在47只近期进口的食蟹猴（猕猴属）中，有20只被发现感染了疟疾。鉴定出的病原体是猪疟原虫。所有感染在本质上都是亚临床的。虫血症范围为每立方毫米全血中有10至900个寄生虫。在用氯喹治疗后评估了治疗前后的血液学值。治疗对清除14只感染猴子中的13只的虫血症有效。与未感染动物相比，感染动物的治疗前血细胞比容、血红蛋白和平均红细胞体积值有显著差异。虽然治疗后的血红蛋白和血细胞比容值恢复到未感染对照水平，但感染动物的平均红细胞体积值在治疗后时期仍显著较低。
