Pietri P, Gabrielli F, Adovasio R
Minerva Chir. 1978;33(15-16):871-8.
Authors stress that multiple carcinomas of the large bowel are not exceptional at all and report 5 cases of metachronous cancers and 1 case of synchronous cancers. They are 4,4% of all the colo-rectal neoplasms operated by the "Istituto di Semeiotica Chirurgica dell'Università di Trieste". The Authors discuss the most important pathogenetic, pathological and diagnostic problems and emphasize the usefulness of a very careful intra-operative evaluation of the entire colon and of a post-operative follow-up for the early discovery and treatment of a second cancer in another tract of the large bowel.
作者强调，大肠多发性癌一点也不罕见，并报告了5例异时性癌和1例同时性癌。它们占的里雅斯特大学外科符号学研究所所做的所有结直肠肿瘤的4.4%。作者讨论了最重要的发病机制、病理学和诊断问题，并强调在术中对整个结肠进行非常仔细的评估以及术后进行随访对于早期发现和治疗大肠另一部位的第二种癌症的有用性。
