Stramba-Badiale M, Scillieri E
Minerva Med. 1983 Apr 7;74(14-15):819-21.
A brief report on the role of neurotransmittors (especially dopamine) depletion in cerebral aging and the development of certain pathological conditions in the elderly is presented. This is followed by a report on the results obtained by the administration of citicoline (500 mg/per diem intramuscularly for 20 days) to a group of 24 elderly patients with senile mental decay. A significant improvement (p less than 0.01) in mental performance was observed in all patients and no side effects were noted.
本文简要报告了神经递质（尤其是多巴胺）耗竭在大脑衰老及老年人某些病理状况发展中的作用。随后报告了对一组24例患有老年精神衰退的老年患者给予胞磷胆碱（每日500毫克，肌肉注射，共20天）后所获得的结果。所有患者的精神表现均有显著改善（p<0.01），且未观察到副作用。
