Stanhope C R, Phibbs G D, Stuart G C, Reid R
Obstet Gynecol. 1983 May;61(5):624-7.
Lower genital tract intraepithelial neoplasia was the predominant indication for CO2 laser surgery in 203 patients treated at Wayne State University. One hundred nineteen patients had cervical intraepithelial neoplasia (CIN) III and, in the 99 patients who were adequately followed, the failure rate following the first treatment was 9%. Secondary treatment with laser surgery, cryosurgery or, in one instance, hysterectomy, was effective in treating all persistent CIN. Success in treating vaginal intraepithelial neoplasia with laser surgery was most favorable in patients who had not had prior pelvic irradiation. Small (less than 1.5 cm) vulvar intraepithelial neoplasia III was successfully treated in seven patients. Recalcitrant condyloma acuminata responded well to laser surgery in 31 patients.
下生殖道上皮内瘤变是韦恩州立大学治疗的203例患者中二氧化碳激光手术的主要适应症。119例患者患有宫颈上皮内瘤变（CIN）III，在99例得到充分随访的患者中，首次治疗后的失败率为9%。激光手术、冷冻手术或1例子宫切除术的二次治疗对所有持续性CIN均有效。对于未接受过盆腔放疗的患者，激光手术治疗阴道上皮内瘤变的成功率最高。7例患者的小（小于1.5 cm）外阴上皮内瘤变III得到成功治疗。31例难治性尖锐湿疣患者对激光手术反应良好。
