Townsend D E, Marks E J
Cancer. 1981 Jul 15;48(2 Suppl):632-7. doi: 10.1002/1097-0142(19810715)48:1+<632::aid-cncr2820481330>3.0.co;2-m.
Over the past decade, the management of intraepithelial lesions of the visible portion of the female genital tract has substantially changed with the introduction of cryosurgery and the carbon dioxide laser. Although cryosurgery and the carbon dioxide laser are very effective in eradicating preinvasive disease, the selection of patients by colposcopy and appropriate biopsies is more important than the treatment techniques. Failure to properly evaluate women with genital tract neoplasia can result in disastrous consequences for the patient. The CO2 laser shows considerable promise in managing dysplasia and carcinoma in situ of the vagina and vulva. The laser combines the accuracy of the operating microscope and the precision and control of the photon beam. Posttreatment sequelae are minimal, and scarring is absent.
在过去十年中，随着冷冻手术和二氧化碳激光的引入，女性生殖道可见部分上皮内病变的管理发生了重大变化。尽管冷冻手术和二氧化碳激光在根除癌前病变方面非常有效，但通过阴道镜检查和适当的活检来选择患者比治疗技术更为重要。未能正确评估患有生殖道肿瘤的女性可能会给患者带来灾难性后果。二氧化碳激光在治疗阴道和外阴发育异常及原位癌方面显示出巨大的前景。该激光结合了手术显微镜的准确性和光子束的精确性及可控性。治疗后的后遗症极少，且不会形成瘢痕。
