Gewolb I H, Freedman R M, Kleinman C S, Hobbins J C
Obstet Gynecol. 1983 May;61(5):657-62.
A unique case is presented of dichorionic-diamnionic twins, one of which contained a primitive heart arrested at an early stage of development and which resembled in many other respects a classic case of acardia. Lack of vascular anastomoses, the dichorionic nature of the twins, and ultrasonic evidence of independent heart rates suggest that the primary pathogenesis in acardia may be cardiac dysmorphogenesis rather than reversal of vascular flow. Ultrasonography and fetal echocardiography proved useful in delineating many of the features of the amorphous twin before delivery.
本文报告了一例独特的双绒毛膜双羊膜囊双胎病例，其中一个胎儿的原始心脏在发育早期停止发育，在许多其他方面类似于无心畸形的典型病例。缺乏血管吻合、双胎的双绒毛膜性质以及独立心率的超声证据表明，无心畸形的主要发病机制可能是心脏形态发生异常，而非血管血流逆转。超声检查和胎儿超声心动图在分娩前明确无定形胎儿的许多特征方面被证明是有用的。
