Musich J R, Behrman S J
Obstet Gynecol. 1978 Jul;52(1):63-6.
A review of 49 patients with uterine anomalies was made to determine the relationship of anomalies to infertility, to obstetric outcome, and to indications for surgical reconstruction (metroplasty). For 41 of the 49 patients with obstetric histories, the overall pregnancy wastage was 72%, with bicornuate and septate patients having 85 to 90% wastage. The 28% of pregnancies that were successful were largely accounted for by patients with didelphic anomalies. It was found that infertility was an uncommon problem in these patients and it should rarely be an indication for metroplasty. In 21 patients properly selected for metroplasty because of repeat pregnancy loss, the obstetric outcome improved from 7% successful pregnancies before surgery to 75% postoperatively. Patients with septate or bicornuate anomalies were found to be poor obstetric performers and likely candidates for repair, while patients with didelphic anomalies achieved obstetric satisfaction without surgical intervention.
对49例子宫异常患者进行了回顾性研究，以确定子宫异常与不孕、产科结局以及手术重建（子宫成形术）指征之间的关系。在49例有产科病史的患者中，有41例，总体妊娠丢失率为72%，双角子宫和纵隔子宫患者的妊娠丢失率为85%至90%。28%的成功妊娠主要由双子宫畸形患者构成。研究发现，不孕在这些患者中并非常见问题，很少应作为子宫成形术的指征。在21例因反复妊娠丢失而被合理选择进行子宫成形术的患者中，产科结局从术前7%的成功妊娠率提高到术后的75%。发现纵隔子宫或双角子宫畸形的患者产科表现较差，可能是修复的合适人选，而双子宫畸形患者无需手术干预即可获得产科满意结局。
