大鼠中千里光、普通千里光和无毛千里光毒性的比较。
Comparison of the toxicities of Senecio jacobaea, Senecio vulgaris and Senecio glabellus in rats.
作者信息
Goeger D E, Cheeke P R, Ramsdell H S, Nicholson S S, Buhler D R
出版信息
Toxicol Lett. 1983 Jan;15(1):19-23. doi: 10.1016/0378-4274(83)90163-7.
The toxicity of Senecio jacobaea, S. vulgaris and S. glabellus to rats was assessed in a feeding trial. The plants were of similar toxicity, with a plant dry matter intake of about 20% of initial body weight being a lethal dose. Gas chromatography-mass spectrometry analysis demonstrated the presence of seneciphylline, jacobine, jacozine and jacoline in S. jacobaea, senecionine and seneciphylline in S. vulgaris, and senecionine in S. glabellus. An unidentified alkaloid was also found in all three plants.
在一项喂养试验中评估了千里光、普通千里光和光果千里光对大鼠的毒性。这些植物具有相似的毒性，摄入约为初始体重20%的植物干物质是致死剂量。气相色谱-质谱分析表明，千里光中存在千里光菲灵碱、雅各布碱、杰可辛和杰可林，普通千里光中存在千里光宁碱和千里光菲灵碱，光果千里光中存在千里光宁碱。在这三种植物中还发现了一种未鉴定的生物碱。
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