卡特赖特（Yt）抗体和盖尔比奇（Ge）抗体的血清学及IgG亚类特征分析

Serologic and IgG subclass characterization of Cartwright (Yt) and Gerbich (Ge) antibodies.

作者信息

Vengelen-Tyler V, Morel P A

出版信息

Transfusion. 1983 Mar-Apr;23(2):114-6. doi: 10.1046/j.1537-2995.1983.23283172845.x.

DOI:10.1046/j.1537-2995.1983.23283172845.x

Abstract

Examples of anti-Yta and anti-Ge were tested for reactivity with red cells treated with proteolytic enzymes and with antisera of known IgG specificity. Eight of 14 examples of anti-Yta did not react as well with cells treated with either papain or ficin; treatment with trypsin did not reduce reactivity. Four examples of the anti-Yta were IgG4; the others tested did not react with IgG subclass antisera. Of 13 examples of anti-Ge, seven failed to react with red cells treated with trypsin, ficin, or papain. Nine examples were IgG1, one was IgG1 plus IgG3, and three did not react with IgG subclass antisera.

摘要

检测了抗Yta和抗Ge的实例与经蛋白水解酶处理的红细胞以及已知IgG特异性抗血清的反应性。14例抗Yta中有8例与木瓜蛋白酶或无花果蛋白酶处理的细胞反应不佳；胰蛋白酶处理并未降低反应性。4例抗Yta为IgG4；其他检测的样本与IgG亚类抗血清无反应。13例抗Ge中，7例与胰蛋白酶、无花果蛋白酶或木瓜蛋白酶处理的红细胞无反应。9例为IgG1，1例为IgG1加IgG3，3例与IgG亚类抗血清无反应。