Frolova I A, Zubenko A D
Vopr Med Khim. 1983 Jan-Feb;29(1):111-5.
Accumulation of 131I was decreased in patients with heart ischemic disease and excessive body mass whereas this decrease occurred more seldom in patients with metabolic-alimenatary obesity. Increase in the ratio of alpha-cholesterol/cholesterol in blood serum was more typical for the patients with heart ischemic disease as compared with corpulent patients. Deterioration of iodine-accumulating function of thyroid gland in the ischemic disease was accompanied by decrease in content of cholesterol as well as by increase of alpha-cholesterol. These alterations were not found in the patients with obesity. In the decrease of iodine-accumulating function of thyroid gland contents of cholesterol and alpha-cholesterol were dissimilarly altered in the patients with excessive body mass and heart ischemic disease as well as in the patients with metabolic-alimentary obesity.
心脏缺血性疾病患者和体重过重患者体内131I的蓄积减少，而这种减少在代谢性营养性肥胖患者中较少发生。与肥胖患者相比，血清中α-胆固醇/胆固醇比值升高在心脏缺血性疾病患者中更为典型。缺血性疾病中甲状腺碘蓄积功能的恶化伴随着胆固醇含量的降低以及α-胆固醇的增加。这些改变在肥胖患者中未发现。在甲状腺碘蓄积功能降低时，体重过重和心脏缺血性疾病患者以及代谢性营养性肥胖患者中胆固醇和α-胆固醇的含量变化不同。
