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肥胖或超重患者的血脂谱

Blood lipids profile in obese or overweight patients.

作者信息

Szczygielska Anna, Widomska Sylwia, Jaraszkiewicz Magdalena, Knera Patrycja, Muc Kamil

机构信息

Students' Scientific Society at the Departament of Cardiology, Medical University of Lublin.

出版信息

Ann Univ Mariae Curie Sklodowska Med. 2003;58(2):343-9.

Abstract

Elevated levels of total and low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are important risk factors for coronary heart disease. Another established predictor of cardiovascular disease is obesity. Obesity and overweight are widespread phenomena and they have reached epidemic proportions in the developed countries, including Poland. Only 30% of people in the Lublin region have normal weight (BMI<25). The aim of this study was to asses the relationship between BMI (body mass index) and blood lipids in the population of 83 people from Aleksandrow commune (64 women and 19 men aged 28-81) who spontaneously applied for medical examination performed as student research. Mean total cholesterol and triglycerides concentrations were higher in obese persons in comparison to normal weight subjects and HDL cholesterol concentration was lower in obese subjects as compared to normal and overweight individuals. Differences in mean concentrations of LDL cholesterol were not significant. A linear correlation between the degree of obesity and plasma level of LDL cholesterol and triglycerides was shown. In conclusion, obesity and overweight are accompanied by unfavourable blood lipids patterns and in a considerable proportion of overweight or obese patients other risk factors for coronary heart disease, such as hypertension, smoking, diabetes or family history of cardiovascular diseases coexist.

摘要

总胆固醇和低密度脂蛋白(LDL)胆固醇水平升高以及高密度脂蛋白(HDL)胆固醇水平降低是冠心病的重要危险因素。另一个已确定的心血管疾病预测指标是肥胖。肥胖和超重是普遍现象,在包括波兰在内的发达国家已达到流行程度。卢布林地区只有30%的人体重正常(体重指数<25)。本研究的目的是评估来自亚历山德罗夫公社的83人(64名女性和19名男性,年龄在28 - 81岁)的人群中体重指数(BMI)与血脂之间的关系,这些人自发申请作为学生研究进行的医学检查。与体重正常的受试者相比,肥胖者的平均总胆固醇和甘油三酯浓度更高,与体重正常和超重的个体相比,肥胖者的HDL胆固醇浓度更低。LDL胆固醇的平均浓度差异不显著。结果显示肥胖程度与LDL胆固醇和甘油三酯的血浆水平之间存在线性相关性。总之,肥胖和超重伴随着不利的血脂模式,并且在相当一部分超重或肥胖患者中,冠心病的其他危险因素,如高血压、吸烟、糖尿病或心血管疾病家族史并存。

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