Tiunov L A, Zhukov V G, Pavlovskiĭ V A, Oleĭnik A I
Vopr Onkol. 1983;29(2):67-71.
The biological (including carcinogenic) effect of an anthraquinone dye sulfoderivative--sulfotrinaphthylenfuran--was studied. The agent displayed low toxicity and cumulation in different species of experimental animals and germ cultures. However, a long-term intoxication by the agent led to tumor formation in the lungs of albino mice, following the pattern of focal reticulosis. The blastogenic effect of sulfotrinaphthylenfuran is suggested.
对蒽醌染料磺衍生物——磺化三萘并呋喃的生物学(包括致癌)效应进行了研究。该制剂在不同种类的实验动物和细菌培养物中显示出低毒性和蓄积性。然而,该制剂的长期中毒导致白化小鼠肺部形成肿瘤,呈现局灶性网状细胞增多症的模式。提示了磺化三萘并呋喃的致有丝分裂作用。