Lazareva I M
Vopr Onkol. 1983;29(2):80-5.
The histological patterns of 120 adenomas and 365 carcinomas of the rectum were established cytologically in accordance with the WHO Histological Classification of Tumours on the basis of morphological, cellular and functional characteristics of neoplasm differentiation. It was found that cytological methods cannot be fully relied upon in the identification of the histological pattern of adenoma. Three degrees of adenoma cell atypia are distinguished: mild, moderate and severe. The latter is more characteristic of villous tumor. The following cytological classification of rectal cancer is suggested: 1. Adenocarcinoma: (a) well-differentiated, (b) moderately-differentiated. 2. Mucinous adenocarcinoma. 3. Signet-ring cell carcinoma. 4. Squamous cell carcinoma: (a) keratinizing, (b) non-keratinizing. 5. Undifferentiated cell carcinoma. 6. Carcinoma (histologically unidentifiable).
根据世界卫生组织肿瘤组织学分类,依据肿瘤分化的形态学、细胞和功能特征,对120例直肠腺瘤和365例直肠癌的组织学类型进行了细胞学判定。结果发现,在腺瘤组织学类型的鉴别中,细胞学方法不能完全依赖。腺瘤细胞异型性分为三度:轻度、中度和重度。后者在绒毛状肿瘤中更具特征性。建议对直肠癌进行如下细胞学分类:1. 腺癌:(a)高分化,(b)中分化。2. 黏液腺癌。3. 印戒细胞癌。4. 鳞状细胞癌:(a)角化型,(b)非角化型。5. 未分化细胞癌。6. 癌(组织学无法鉴别)。