Sorensen E M, Harlan C W, Bell J S, Bauer T L, Pradzynski A H
Am J Forensic Med Pathol. 1983 Mar;4(1):25-32. doi: 10.1097/00000433-198303000-00004.
This report provides morphological and analytical data for a group of green sunfish collected from an area relatively free of metals and a second group of the same species collected from a lake into which selenium had been discharged. Neutron activation data of livers (and kidneys) collected from these fish show an average of about 11 ppm selenium (fresh weight) for both organs; other metals were not detected in the liver (or kidneys) of these fish. Ultrastructural examination of livers from fish of this group showed focal necrosis, areas of granular cytoplasm, fatty infiltration, increased numbers of Kupffer cells, and disorganized liver architecture--compared with those of controls. The presence of massive levels of selenium in the liver and concomitant hepatocyte changes suggests a causal relationship between these phenomena.
本报告提供了两组绿太阳鱼的形态学和分析数据。一组是从一个相对无金属污染的区域采集的，另一组是从一个已排放硒的湖泊中采集的同一物种。从这些鱼的肝脏（和肾脏）收集的中子活化数据显示，这两个器官的硒平均含量约为11 ppm（鲜重）；在这些鱼的肝脏（或肾脏）中未检测到其他金属。与对照组相比，对该组鱼的肝脏进行超微结构检查发现有局灶性坏死、颗粒状细胞质区域、脂肪浸润、库普弗细胞数量增加以及肝脏结构紊乱。肝脏中大量硒的存在以及伴随的肝细胞变化表明这些现象之间存在因果关系。
