Young R H, Dickersin G R, Scully R E
Am J Surg Pathol. 1983 Apr;7(3):233-43. doi: 10.1097/00000478-198304000-00002.
Two distinctive ovarian tumors that caused sexual precocity in young girls with the Peutz-Jeghers syndrome are described. Each of the tumors varied in its histologic pattern, with diffuse areas, foci of tubular differentiation, microcysts and papillae, and contained two unusual cell types. The light-microscopic and ultrastructural findings were consistent with a hitherto undescribed form of sex cord-stromal tumor. The unique microscopic appearance of this tumor and its association with the Peutz-Jeghers syndrome in both cases suggest that it is a third type of gynecological neoplasm related to that disorder.
本文描述了两种独特的卵巢肿瘤，它们在患有佩-吉综合征的年轻女孩中导致性早熟。每种肿瘤的组织学模式各不相同，有弥漫区域、管状分化灶、微囊肿和乳头，并包含两种不寻常的细胞类型。光镜和超微结构检查结果与一种迄今未描述过的性索间质肿瘤形式一致。该肿瘤独特的显微镜下表现及其在两例病例中与佩-吉综合征的关联表明，它是与该疾病相关的第三种妇科肿瘤类型。
