Herbold D R, Fu Y S, Silbert S W
Am J Surg Pathol. 1983 Apr;7(3):285-92.
A case of leiomyosarcoma arising in a preexisting leiomyoma of the broad ligament is presented with ultrastructural and Feulgen microspectrophotometric confirmation. This is the fourth reported case of leiomyosarcoma of the broad ligament and the second reported case to show evidence of a preexisting leiomyoma. Three of these patients died after intervals of 1, 7, and 19 months; one is alive and well with no evidence of disease after 12 years. The definitive evidence of malignant transformation of a leiomyoma has particular relevance to the controversy regarding the relationship of uterine leiomyosarcomas and leiomyomas.
本文报告1例发生于阔韧带平滑肌瘤的平滑肌肉瘤，并经超微结构和福尔根显微分光光度法证实。这是第4例报道的阔韧带平滑肌肉瘤，也是第2例有证据表明存在先前平滑肌瘤的病例。其中3例患者分别在1个月、7个月和19个月后死亡；1例患者在12年后仍存活且状况良好，无疾病迹象。平滑肌瘤恶性转化的确切证据与子宫平滑肌肉瘤和平滑肌瘤关系的争议特别相关。
