Hutchison K J, Overton T R, Biltek K B, Nixon R, Williams H T
Angiology. 1983 Apr;34(4):223-30. doi: 10.1177/000331978303400401.
The increase in skin blood flow produced by both reactive hyperemia and histamine was examined in 8 normal, 8 diabetic and 3 cancer patients using the epicutaneous Xenon-133 clearance method. The histamine flare response in both diabetic and cancer groups was reduced compared to that in the normal group. There was no significant difference in the reactive hyperemia responses. It is concluded that the reduction in the histamine flare response is due to a defect in the sensory nerves mediating the axon reflex and not due to a change in the vascular response.
采用经皮氙 - 133清除法，对8名正常受试者、8名糖尿病患者和3名癌症患者的皮肤血流因反应性充血和组胺引起的增加情况进行了研究。与正常组相比，糖尿病组和癌症组的组胺潮红反应均降低。反应性充血反应无显著差异。得出的结论是，组胺潮红反应的降低是由于介导轴突反射的感觉神经缺陷，而非血管反应的改变。
