Partamian L G, Jay W M, Fritz K J
Ann Ophthalmol. 1983 Feb;15(2):123-6.
A 10-year-old boy with orbital cellulitis died seven weeks after admission to the hospital despite intensive surgical intervention and medical therapy. We isolated many anaerobic bacteria from the orbit, frontal sinus, and epidural space. Orbital cellulitis, which often occurs by direct extension from infected paranasal sinuses, commonly affects children and young adults, and is a potentially lethal disease, if left untreated. Heightened awareness of the role of anaerobes in chronic sinusitis and of the possibility of an anaerobic orbital cellulitis may lead to the identification of more cases. Penicillin G appears to be the first drug of choice in cases with suspected anaerobic orbital cellulitis. Chloramphenicol and clindamycin should be considered, if treatment with penicillin fails. Antibiotics alone should not be considered as a panacea, and surgical drainage is often the most compelling consideration.
一名患有眼眶蜂窝织炎的10岁男孩在入院七周后死亡，尽管接受了强化手术干预和药物治疗。我们从眼眶、额窦和硬膜外间隙分离出许多厌氧菌。眼眶蜂窝织炎通常由感染的鼻窦直接蔓延引起，常见于儿童和年轻人，若不治疗，是一种潜在的致命疾病。提高对厌氧菌在慢性鼻窦炎中的作用以及厌氧性眼眶蜂窝织炎可能性的认识，可能会发现更多病例。对于疑似厌氧性眼眶蜂窝织炎的病例，青霉素G似乎是首选药物。如果青霉素治疗失败，应考虑使用氯霉素和克林霉素。不应将抗生素单独视为万灵药，手术引流往往是最关键的考虑因素。
