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将兔子长期暴露于0.5和5毫瓦/平方厘米的2450兆赫连续波微波辐射下。

Chronic exposure of rabbits to 0.5 and 5 mW/cm2 2450-MHz CW microwave radiation.

作者信息

Chou C K, Guy A W, Borneman L E, Kunz L L, Kramar P

出版信息

Bioelectromagnetics. 1983;4(1):63-77. doi: 10.1002/bem.2250040107.

Abstract

Two groups of 16 male New Zealand rabbits were exposed to 2450-MHz continuous wave microwave fields in two experiments of 90 days each. The incident power densities of the first and second experiment were 0.5 and 5 mW/cm2, respectively. During each study, 16 animals were adapted to a miniature anechoic chamber exposure system for at least 2 weeks, then 8 of them were exposed for 7 h daily, 5 days a week for 13 weeks, and the other 8 animals were sham exposed. The rabbits were placed in acrylic cages, and each was exposed from the top in an individual miniature anechoic chamber. Thermography showed a maximum specific absorption rate of 5.5 W/kg in the head and 7 W/kg in the back at 5-mW/cm2 incident power density. After each 7-h exposure session, the animals were returned to their home cages. Food consumption in the exposure chamber and body mass were measured daily. Blood samples were taken before exposure and monthly thereafter for hematological, morphological, chemical, protein electrophoresis, and lymphocyte blast transformation studies. Eyes were examined for cataract formation. Finally, pathological examinations of 28 specimens of organs and tissues of each rabbit were performed. Statistically, there was a significant (P less than .01) decrease only of food consumption during the 5-mW/cm2 exposure; other variables were not significantly different between exposed and control groups.

摘要

在两项为期90天的实验中,两组各16只雄性新西兰兔暴露于2450兆赫的连续波微波场中。第一项和第二项实验的入射功率密度分别为0.5和5毫瓦/平方厘米。在每项研究中,16只动物在微型消声室暴露系统中适应至少2周,然后其中8只动物每天暴露7小时,每周5天,持续13周,另外8只动物进行假暴露。兔子被放置在丙烯酸笼子里,每只兔子在单独的微型消声室内从顶部接受暴露。热成像显示,在入射功率密度为5毫瓦/平方厘米时,头部的最大比吸收率为5.5瓦/千克,背部为7瓦/千克。每次7小时的暴露结束后,动物被放回它们的笼舍。每天测量暴露室内的食物消耗量和体重。在暴露前以及此后每月采集血样,用于血液学、形态学、化学、蛋白质电泳和淋巴细胞增殖转化研究。检查眼睛是否形成白内障。最后,对每只兔子的28个器官和组织标本进行病理检查。从统计学角度来看,仅在5毫瓦/平方厘米暴露期间食物消耗量有显著(P小于0.01)下降;暴露组和对照组之间的其他变量没有显著差异。

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