Wiemann M C, Calabresi P
Compr Ther. 1983 Mar;9(3):46-52.
Cancer chemotherapy is an established therapeutic modality capable of achieving cures, either alone or in combination with surgery and radiation therapy. New drugs and therapeutic approaches with potent effects on both tumor and normal host tissues are being introduced into clinical use. Clinical management of the patient with cancer, however, continues to be based upon established principles. Knowledge of these principles will guide the clinician in the appropriate use of the growing list of effective chemotherapeutic agents. Although standard therapy for specific tumors will undoubtedly change during the next few years, future therapy will still be founded on fundamental concepts and basic principles of tumor biology and clinical oncology.
癌症化疗是一种既定的治疗方式，单独使用或与手术及放射治疗联合使用时都能够实现治愈。对肿瘤和正常宿主组织均有强效作用的新药及治疗方法正被引入临床应用。然而，癌症患者的临床管理仍基于既定原则。了解这些原则将指导临床医生合理使用越来越多的有效化疗药物。尽管特定肿瘤的标准治疗在未来几年无疑会发生变化，但未来的治疗仍将基于肿瘤生物学和临床肿瘤学的基本概念和基本原则。
