Polotniuk N A, Detiuk E S
Probl Endokrinol (Mosk). 1978 Jul-Aug;24(4):81-6.
Experiments were conducted on rats; morphofunctional changes of the thyroid gland in correction of iodine and bromine deficiency, depending on the regimen of the microelements administration in the course of a one-week cycle were studied. Daily administration of a one-week dose of iodine and bromine proved to be most effective in respect to the normalization of the morphofunctional condition of the thyroid gland in animals given iodine-deficient diet. The lowest thyroid gland weight, intensification of the synthetic processes in the thyrocytes, complete utilization of the thyroid gland iodine, and enrichment of the organism with trace elements were noted. Recommendations are given concerning the expediency of the change of regimen of iodine and bromine administration in group antigoiter prophylaxis.
在大鼠身上进行了实验；研究了在为期一周的周期内，根据微量元素给药方案，纠正碘和溴缺乏时甲状腺的形态功能变化。对于给予缺碘饮食的动物，每日给予一周剂量的碘和溴被证明在使甲状腺形态功能状况正常化方面最为有效。观察到甲状腺重量最低、甲状腺细胞合成过程增强、甲状腺碘完全利用以及机体微量元素富集。就抗甲状腺肿预防组中碘和溴给药方案改变的适宜性给出了建议。
