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[神经醇和肠内氧疗在实验性肝营养不良中的疗效]

[Effectiveness of nerobol and enteral oxygen therapy in experimental liver dystrophy].

作者信息

Kornienko G F

出版信息

Probl Endokrinol (Mosk). 1978 Jul-Aug;24(4):92-7.

PMID:683981
Abstract

Experiments were conducted on 115 female albino rats; a study was made of the efficacy of nerobol and enteral oxygen therapy in acute dystrophy of the liver on the 7th and 14th days after the beginning of carbon tetrachloride administration. The use of nerobol, particularly in its combination with oxygen therapy, favoured gain in weight of the animals, improved their general condition, accelerated normalization of hepatic functions. Treatment promoted more rapid and complete restoration of the intensity of bile secretion, enhanced the synthesis of free bile acids, and also their conjugation with glycine and taurine. When combined with enteral oxygen therapy the efficacy of nerobol increased considerably.

摘要

对115只雌性白化大鼠进行了实验;研究了在给予四氯化碳后的第7天和第14天,尼乐宝和肠内氧疗对急性肝营养不良的疗效。使用尼乐宝,尤其是将其与氧疗联合使用,有利于动物体重增加,改善其一般状况,加速肝功能正常化。治疗促进胆汁分泌强度更快、更完全地恢复,增强游离胆汁酸的合成,以及它们与甘氨酸和牛磺酸的结合。当与肠内氧疗联合使用时,尼乐宝的疗效显著提高。

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