Murata K
Gerontology. 1983;29(2):131-9. doi: 10.1159/000213105.
3 cases of Werner's syndrome were studied on serum lipid metabolism in comparison with clinical manifestation. These 3 cases showed hyperlipemia all with hypertriglycemia and increased level of very low density lipoprotein. The lipoprotein lipase activity was shown after intravenous injection of heparin. These results indicate a possible pathogenic facet of Werner's syndrome from the lipid metabolic point of view.
对3例沃纳综合征患者的血脂代谢进行了研究,并与临床表现进行了比较。这3例患者均表现为高脂血症,均伴有高甘油三酯血症和极低密度脂蛋白水平升高。静脉注射肝素后显示脂蛋白脂肪酶活性。这些结果从脂质代谢的角度表明了沃纳综合征可能的致病方面。