纤溶酶原遗传系统中活性与血浆浓度表型的比较研究。

Comparative study of phenotypes on activity and plasma concentration in the genetic system of plasminogen.

作者信息

Kera Y, Nishimukai H, Yamasawa K, Komura S

出版信息

Hum Hered. 1983;33(1):52-4. doi: 10.1159/000153347.

Abstract

Plasma antigen concentration of plasminogen was approximately 11-13 mg/100 ml in all phenotypes. Specific activities of common PLG 1-1 and second common PLG 2-1 were 16.52 +/- 1.43 U/mg (caseinolytic activity/milligram antigen concentration, mean +/- SD) and 17.22 +/- 2.14 U/mg, respectively. Caseinolytic activity, antigen concentration and specific activity of PLG 1-B were 0.80 +/- 0.23 U/ml, 11.39 +/- 2.44 mg/100 ml and 6.95 +/- 0.96 U/mg. Plasma plasminogen levels of three rare phenotypes (PLG 3-1, PLG 1-C and PLG 1-M) were at least in the normal ranges by immunological and biological assay.

摘要

在所有表型中，血浆纤溶酶原抗原浓度约为11 - 13毫克/100毫升。常见PLG 1-1和第二常见PLG 2-1的比活性分别为16.52±1.43 U/毫克（酪蛋白溶解活性/毫克抗原浓度，平均值±标准差）和17.22±2.14 U/毫克。PLG 1-B的酪蛋白溶解活性、抗原浓度和比活性分别为0.80±0.23 U/毫升、11.39±2.44毫克/100毫升和6.95±0.96 U/毫克。通过免疫和生物学检测，三种罕见表型（PLG 3-1、PLG 1-C和PLG 1-M）的血浆纤溶酶原水平至少在正常范围内。