Cebrián M E, Albores A, Aguilar M, Blakely E
Hum Toxicol. 1983 Jan;2(1):121-33. doi: 10.1177/096032718300200110.
1 We compared the prevalence of signs and symptoms of chronic arsenic poisoning in two rural populations. 2 The arsenic concentration in the drinking water of the exposed population was 0.41 mg/l, and 0.007 mg/l in the control population. 3 The arsenic was present mainly (70%) in its pentavalent form. 4 The objective was to quantitate health effects and risks derived from chronic ingestion of arsenic in contaminated water. 5 In the exposed population, 21.6% of the sample, showed at least one of the cutaneous signs of chronic arsenic poisoning against 2.2% in the control town. 6 Non-specific symptoms were more prevalent in the exposed population and they occurred more frequently in those individuals with skin signs. 7 The relative risk of suffering a particular manifestation of poisoning, ranged from 1.9 to 36 times higher in the exposed population. 8 We estimated the risks above mentioned, which were derived from exposure to minute quantities of arsenic in a known proportion of its oxidation states during a life time period.
我们比较了两个农村人群中慢性砷中毒体征和症状的患病率。
暴露人群饮用水中的砷浓度为0.41毫克/升，对照人群为0.007毫克/升。
砷主要以五价形式存在（70%）。
目的是量化长期摄入受污染水中的砷所产生的健康影响和风险。
在暴露人群中，21.6%的样本至少出现了一种慢性砷中毒的皮肤体征，而对照城镇为2.2%。
非特异性症状在暴露人群中更为普遍，且在有皮肤体征的个体中出现得更频繁。
暴露人群中出现特定中毒表现的相对风险比对照人群高1.9至36倍。
我们估计了上述风险，这些风险源于在一生中接触已知氧化态比例的微量砷。
