Armstrong C W, Stroube R B, Rubio T, Siudyla E A, Miller G B
Arch Environ Health. 1984 Jul-Aug;39(4):276-9. doi: 10.1080/00039896.1984.10545849.
An outbreak of subacute poisoning occurred among nine members of a family; eight were ill with gastrointestinal symptoms, four developed encephalopathy, and two died. Abnormal liver function tests and leukopenia were common laboratory findings. Epidemiologic and environmental investigations traced the source of arsenic exposure to a farm well with water containing 108 ppm arsenic. The soil adjacent to the well was also contaminated with arsenic, possibly from waste pesticide. Presumably, arsenic gained access to the well through obvious leaks in the well's casing. To our knowledge, this is only the second reported outbreak of fatal arsenic poisoning from contaminated drinking water and one of few instances where illness followed exposure to a toxic substance which was disposed of, or possibly disposed of, in an indiscriminate manner.
一个家庭的九名成员中发生了亚急性中毒事件；八人出现胃肠道症状，四人发展为脑病，两人死亡。肝功能检查异常和白细胞减少是常见的实验室检查结果。流行病学和环境调查追踪到砷暴露源是一口农场水井，井水中砷含量为108 ppm。水井附近的土壤也被砷污染，可能来自废弃农药。据推测，砷是通过水井套管的明显泄漏进入水井的。据我们所知，这是第二例报告的因受污染饮用水导致的致命砷中毒事件，也是少数几起因接触以随意方式处置或可能已被处置的有毒物质而发病的案例之一。
