Pizzarelli F, Sisca S, Zoccali C, Parlongo S, Nicolò F, Creazzo G, Delfino D, Maggiore Q
Int J Artif Organs. 1983 Jan;6(1):37-41.
Temperature (T) changes in the blood flowing through the extracorporeal circuit markedly affect cardiovascular tolerance to fluid removal during either hemodialysis (HD) and isolated ultrafiltration. In this study we investigated the effect of blood T changes during postdilutional hemofiltration (HF). To this purpose we compared the changes in mean arterial pressure (MAP) and heart rate (HR) during HF and HD carried out at equivalent T of blood in the venous segment of the extracorporeal circuit. Results show that HF entails some heat loss from blood flowing in the extracorporeal circuit; if heat loss is made similar, HD affords nearly as much blood pressure protection as HF does. On the other hand at equivalent heat gain, HF causes nearly as much hypotension as HD does. We conclude that blood T changes in the extracorporeal circuit affect vascular stability (VS) even in HF. The marginal benefit of HF over HD, still observed at equalized T changes, remains to be elucidated.
在血液透析（HD）和单纯超滤过程中，流经体外循环的血液温度（T）变化显著影响心血管系统对液体清除的耐受性。在本研究中，我们调查了后稀释血液滤过（HF）过程中血液T变化的影响。为此，我们比较了在体外循环静脉段血液T值相当的情况下进行HF和HD时平均动脉压（MAP）和心率（HR）的变化。结果表明，HF会导致体外循环中流动的血液出现一定热量损失；如果热量损失相似，HD提供的血压保护作用与HF几乎相同。另一方面，在热量增加相当的情况下，HF导致的低血压程度与HD几乎相同。我们得出结论，即使在HF中，体外循环中的血液T变化也会影响血管稳定性（VS）。在T变化均衡的情况下仍能观察到的HF相对于HD的边际益处，仍有待阐明。
