Lemp M A, Weiler H H
Invest Ophthalmol Vis Sci. 1983 May;24(5):619-22.
The mechanisms of tear flow, blinking, and tear drainage were studied employing high speed slit-lamp cinematography using a polystyrene microsphere suspension as a tracer of tear movement. It was demonstrated that: (1) Tears are drawn into the canaliculi during the relaxation phase of blinking. (2) Both superior and inferior puncta function as normal tear drainage routes. (3) The superior punctum alone is sufficient to handle tear drainage. (4) There is some regurgitation of tears from the canaliculi. (5) An intact blink mechanism is necessary for effective tear drainage. (6) There is an actual closure of the puncta during blinking. This is sufficient to effect tear exit without the lids meeting. The clinical impression that in order to effectively prevent tear drainage in the treatment of dry eyes, it is necessary to occlude both the superior and inferior puncta was confirmed.
采用高速裂隙灯电影摄影术，以聚苯乙烯微球悬液作为泪液运动的示踪剂，对泪液流动、眨眼和泪液引流机制进行了研究。结果表明：（1）在眨眼的松弛阶段，泪液被吸入泪小管。（2）上、下泪点均作为正常的泪液引流途径。（3）仅上泪点就足以处理泪液引流。（4）泪小管存在一些泪液反流。（5）完整的眨眼机制对于有效的泪液引流是必要的。（6）眨眼时泪点实际会闭合。这足以在眼睑不接触的情况下实现泪液排出。证实了临床上的一种观点，即在干眼症治疗中，为有效防止泪液引流，有必要同时封闭上、下泪点。
