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人类白细胞抗原与生殖?

HLA and reproduction?

作者信息

Giphart M J, D'Amaro J

出版信息

J Immunogenet. 1983 Feb;10(1):25-9. doi: 10.1111/j.1744-313x.1983.tb01013.x.

DOI:10.1111/j.1744-313x.1983.tb01013.x
PMID:6841981
Abstract

In mice it has been shown that mating preference is genetically associated with the Major Histocompatibility Complex (MHC). In the present study, an approach is described to study homologous aspects of the MHC in man. After selection of families with one or more children, a given parental HLA antigen was selected and the frequencies of the spouse's HLA antigens were determined. Assuming a random distribution, these frequencies should not be statistically different from those of the total population. Evidence is presented that this distribution is not random for a number of maternal and paternal HLA antigens.

摘要

在小鼠中已表明,交配偏好与主要组织相容性复合体(MHC)存在遗传关联。在本研究中,描述了一种研究人类MHC同源方面的方法。在选择有一个或多个孩子的家庭后,选择一种给定的亲本HLA抗原,并确定配偶的HLA抗原频率。假设为随机分布,这些频率在统计学上应与总人口的频率无差异。有证据表明,对于一些母本和父本HLA抗原,这种分布并非随机。

相似文献

1
HLA and reproduction?人类白细胞抗原与生殖?
J Immunogenet. 1983 Feb;10(1):25-9. doi: 10.1111/j.1744-313x.1983.tb01013.x.
2
The effect of parental HLA compatibility on the expression of paternal haplotypes in offspring.
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3
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引用本文的文献

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Philos Trans R Soc Lond B Biol Sci. 2020 Jun 8;375(1800):20190260. doi: 10.1098/rstb.2019.0260. Epub 2020 Apr 20.
2
Influence of HLA on human partnership and sexual satisfaction.HLA 对人类伴侣关系和性满足的影响。
Sci Rep. 2016 Aug 31;6:32550. doi: 10.1038/srep32550.
3
Smelling phenomenal.闻起来棒极了。
Front Psychol. 2014 Jul 10;5:713. doi: 10.3389/fpsyg.2014.00713. eCollection 2014.
4
Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset.气味受体家族 13 和 MHC 基因座的遗传变异影响多发性硬化症数据集的配偶选择。
BMC Genomics. 2010 Nov 10;11:626. doi: 10.1186/1471-2164-11-626.
5
No role of HLA in mate selection.HLA在配偶选择中无作用。
Immunogenetics. 1983;18(4):429-31. doi: 10.1007/BF00372474.