Brunner H, Weidner W, Schiefer H G
J Infect Dis. 1983 May;147(5):807-13. doi: 10.1093/infdis/147.5.807.
It has definitely been demonstrated that Ureaplasma urealyticum is one etiologic agent of nongonococcal urethritis, a sexually transmitted disease. For this reason it seemed possible that the organisms might cause ascending inflammatory reactions of the prostate. Quantitative determinations of ureaplasmas and Mycoplasma hominis, together with localization studies, were therefore performed to elucidate the importance of these microorganisms in patients with chronic prostatitis. U. urealyticum was found in high numbers in expressed prostatic secretions and urine voided after prostatic massage from 82 (13.7%) of 597 patients with chronic prostatitis. Because numbers of ureaplasmas in first-voided urine and midstream urine were significantly lower, the source of the organisms in these patients was assumed to be the prostate. These data and the results of tetracycline treatment provide sufficient evidence for the etiologic importance of ureaplasmas in chronic prostatitis.
已明确证实解脲脲原体是一种性传播疾病——非淋菌性尿道炎的病原体之一。因此，这些微生物有可能引发前列腺的上行性炎症反应。为此，进行了解脲脲原体和人型支原体的定量测定以及定位研究，以阐明这些微生物在慢性前列腺炎患者中的重要性。在597例慢性前列腺炎患者中，有82例（13.7%）在前列腺按摩后排出的前列腺分泌物和尿液中发现大量解脲脲原体。由于首次晨尿和中段尿中的解脲脲原体数量明显较低，推测这些患者体内的病原体来源是前列腺。这些数据以及四环素治疗的结果为解脲脲原体在慢性前列腺炎中的病因学重要性提供了充分证据。
