Jakle C, Leek J C, Olson D A, Robbins D L
J Rheumatol. 1983 Feb;10(1):151-3.
A case of Fusarium arthritis is reported. Fusarium, a mold ubiquitous in soil and on plants commonly causes keratomycosis and infects burns. Recent reports demonstrate that Fusarium may produce serious visceral infection in compromised hosts. Disseminated infection has been universally fatal. In contrast, our case and several others with localized visceral infection were cured by intravenous amphotericin B and drainage. Although Fusarium grows readily on mycologic media, blood and other cultures have usually been negative in disseminated infection. Physicians should be aware of this uncommon but potentially lethal pathogen because deep fungal infections may first appear as arthritis.
报告了一例镰刀菌关节炎病例。镰刀菌是一种在土壤和植物中普遍存在的霉菌，通常会引起角膜真菌病并感染烧伤创面。最近的报告表明，镰刀菌可能在免疫功能低下的宿主中引起严重的内脏感染。播散性感染通常是致命的。相比之下，我们的病例以及其他几例局限性内脏感染病例通过静脉注射两性霉素B和引流得以治愈。尽管镰刀菌在真菌培养基上易于生长，但在播散性感染中，血液和其他培养物通常为阴性。医生应意识到这种罕见但可能致命的病原体，因为深部真菌感染可能最初表现为关节炎。
