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Preliminary crystallographic study of the Fab fragment of a monoclonal anti-phenylarsonate antibody.

作者信息

Amit A G, Harper M M, Mariuzza R A, Saludjian P, Poljak R J, Lamoyi E, Nisonoff A

出版信息

J Mol Biol. 1983 Apr 5;165(2):415-7. doi: 10.1016/s0022-2836(83)80266-6.

Abstract

Preliminary crystallographic data are given for the Fab fragment of a monoclonal anti-p-phenylarsonate antibody. This crystalline Fab fragment was found by screening a number of monoclonal anti-arsonate antibodies obtained from hybrids of A/J immune spleen cells with a non-secreting mouse myeloma line. The protein crystallizes in the monoclinic space group P21 with a = 86.2 +/- 0.1 A, b = 80.4 +/- 0.2 A, c = 75.8 +/- 0.1 A, beta = 90.3 +/- 0.1 degrees. Precession photographs show X-ray reflections extending to a resolution of 3 A.

摘要

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