Vakaliuk P M, Shvedenko L A, Nikulin K E, Iurkevich S T, Gerasimenko N I, Kozak V P
Kardiologiia. 1983 Feb;23(2):61-5.
A total of 58 patients were treated with adelphane-esidrex for hypertension, Stage II. Their general condition improved considerably and arterial blood pressure obviously decreased. The hypotensive effect of the treatment was associated with a considerable fall of high systemic peripheral resistance in most patients, and with reduced systolic and minute blood volume in others. An improvement was noted in the phasic pattern of left and right ventricular systole, pulmonary circulation, external respiratory function and also microcirculation.
共有58例二期高血压患者接受了萝芙木总碱-依西多来治疗。他们的一般状况有了显著改善,动脉血压明显下降。该治疗的降压效果与大多数患者全身外周阻力显著降低有关,而在其他患者中与收缩期和每分血容量减少有关。左、右心室收缩的相位模式、肺循环、外呼吸功能以及微循环均有改善。