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膜状生物组织的力学特性

Mechanical characterization of membranelike biological tissue.

作者信息

Thibault L E, Fry D L

出版信息

J Biomech Eng. 1983 Feb;105(1):31-8. doi: 10.1115/1.3138381.

DOI:10.1115/1.3138381
PMID:6843099
Abstract

Experimental and analytical methods are presented which enable one to examine the local rheological properties of biological tissues which can be captured as flat sheets between matching pressure manifolds and deformed under experimentally prescribed hydrostatic loading conditions. In spite of the fact that most biological tissues, including arteries, are nonlinearly elastic when considered over wide ranges of strain, it was found that the deformation of swine and canine arterial wall specimens in the physiological range of wall strain can be approximated by an isotropic, linearily elastic membrane model. In view of this, the elastic behavior was characterized approximately by an incremental modulus over the range of 0.45 to 0.65 strain. The incremental modulus in both species was shown to increase by a factor of three along the descending thoracic aorta from the ductus scar to the celiac orifice.

摘要

本文介绍了实验和分析方法,这些方法能够让人检查生物组织的局部流变特性,这些生物组织可以在匹配的压力歧管之间被捕获为平板,并在实验规定的静水加载条件下发生变形。尽管包括动脉在内的大多数生物组织在较大应变范围内被认为是非线性弹性的,但研究发现,猪和犬动脉壁标本在生理壁应变范围内的变形可以用各向同性的线性弹性膜模型来近似。鉴于此,弹性行为在0.45至0.65应变范围内大致用增量模量来表征。结果表明,在这两个物种中,从动脉导管瘢痕到腹腔口,沿降主动脉增量模量增加了两倍。

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Mechanical characterization of membranelike biological tissue.膜状生物组织的力学特性
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An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex.一种用乳胶验证的测量大鼠肺动脉力学性能的实验方法。
J Res Natl Inst Stand Technol. 2003 Jun 1;108(3):183-91. doi: 10.6028/jres.108.018. Print 2003 May-Jun.
2
Strain measurements in cultured vascular smooth muscle cells subjected to mechanical deformation.对经受机械变形的培养血管平滑肌细胞进行应变测量。
Ann Biomed Eng. 1994 Jan-Feb;22(1):14-22. doi: 10.1007/BF02368218.