Pritchard E T, Chan A C
Lipids. 1983 Feb;18(2):146-8. doi: 10.1007/BF02536110.
The effect of feeding diets containing various levels of vitamin E for 6 months on the in vitro synthesis of sulfolipids in rat submandibular salivary glands (SMG) was elucidated. The incorporation of [35S]sulfate into sulfolipid of SMG from rats on deficient or "normal" vitamin E diets was quite similar, however, the uptake was significantly increased in glands from rats on diets high in vitamin E. Whereas, in many instances, antioxidants can mimic the effect of vitamin E, in the present study, the antioxidant N,N'-diphenyl-p-phenylene diamine (DPPD) was actually found significantly to depress sulfolipid-labeling below that noted in SMG from all other diets. The results suggest that in the synthesis of SMG sulfolipid the action of vitamin E may be more than that of a simple antioxidant.
阐明了给大鼠喂食含不同水平维生素E的日粮6个月对大鼠下颌下唾液腺（SMG）中硫脂体外合成的影响。来自缺乏维生素E或“正常”维生素E日粮大鼠的SMG中，[35S]硫酸盐掺入硫脂的情况相当相似，然而，来自高维生素E日粮大鼠的腺体中摄取量显著增加。虽然在许多情况下抗氧化剂可模拟维生素E的作用，但在本研究中，实际上发现抗氧化剂N,N'-二苯基对苯二胺（DPPD）显著降低硫脂标记，低于所有其他日粮组SMG中的标记。结果表明，在SMG硫脂合成中，维生素E的作用可能不仅仅是简单的抗氧化作用。
