Blake T R, Gross J F
Microvasc Res. 1983 Mar;25(2):156-75. doi: 10.1016/0026-2862(83)90012-2.
A theoretical model, appropriate for data interpretation, is presented for the transcapillary fluid exchange and associated intraluminal hydrodynamic and solute transport occurring in the microocclusion of single capillaries. This analysis describes the spatial and temporal behavior of the intraluminal flow. A comparison of the theory with in vivo data suggests good qualitative agreement with that data and, further, the specification of filtration parameters in the model leads to good quantitative agreement regarding the displacement histories of erythrocytes. The model includes both natural and tagged colloidal osmotic influences and can, therefore, be used to represent experiments wherein the concentration of a dyed colloid is measured and related to fluid filtration. The relative merits of measuring colloidal concentration or erythrocyte displacement are discussed within the context of the model.
针对单根毛细血管微阻塞时发生的跨毛细血管液体交换以及相关的管腔内流体动力学和溶质转运，提出了一个适用于数据解释的理论模型。该分析描述了管腔内流动的时空行为。理论与体内数据的比较表明，二者在定性上吻合良好，此外，模型中过滤参数的设定使得在红细胞位移历程方面达成了良好的定量吻合。该模型包含天然和标记的胶体渗透压影响，因此可用于表示测量染色胶体浓度并将其与液体过滤相关联的实验。在模型的背景下讨论了测量胶体浓度或红细胞位移的相对优点。
