Petitclerc T, Man N K, Sausse A, Funck-Brentano J L
Nephrologie. 1983;4(1):21-3.
In hemodialysis, an excessive oversimplification leads to confuse the transfer direction of a given solute (patient towards dialysate or dialysate towards patient) and the direction of transmembranar concentration gradient. Applied to sodium, this confusion leads to the usual iso- or hypotonic dialysate use, in order to eliminate the patient's sodium overload. We show here how the use of a high sodium dialysate allows the elimination of the sodium overload and makes the free water clearance (approached by the Na-free water clearance) positive, which is the necessary condition to restore an hydro-electrolytic equilibrium near from the normal. That allows a disappearance of hypovolemic symptoms during hemodialysis, a better general condition and a possible increase of water intake between sessions.
在血液透析中，过度简化会导致混淆特定溶质的转运方向（从患者到透析液或从透析液到患者）以及跨膜浓度梯度的方向。应用于钠时，这种混淆导致通常使用等渗或低渗透析液，以消除患者的钠超载。我们在此展示了使用高钠透析液如何能够消除钠超载，并使自由水清除率（通过无钠自由水清除率来近似）变为正值，这是恢复接近正常的水电解质平衡的必要条件。这使得血液透析期间低血容量症状消失，整体状况改善，并且两次透析之间可能增加水的摄入量。
