Herron P
Neuroscience. 1983;8(2):243-57. doi: 10.1016/0306-4522(83)90063-5.
The thalamocortical afferents to cortical somatosensory areas I (SI) and II (SII) were investigated in the raccoon using the horseradish peroxidase technique. The purpose of this study was to determine if the cell bodies of origin for thalamocortical afferents to these cortical regions were localized in the same or different nuclei in the ventroposterior region of the thalamus. Horseradish peroxidase was injected into subdivisions of SI or SII and after post-injection survival periods of 12-72 hours the horseradish peroxidase in the tissue was reacted with the chromogens dihydrochlorobenzidine or tetramethylbenzidine in the presence of hydrogen peroxide. The results show that SI and SII receive projections from neurons in separate and distinct nuclei in the ventroposterior thalamus. Following injections into subdivisions of area I, a topographical distribution of retrogradely-labelled cell bodies was observed in the ventrobasal complex. Following injections of horseradish peroxidase into subdivisions of area II, a topographical distribution of labelled cell bodies was observed in the ventroposterior inferior nucleus. No labelled cell bodies were observed in the ventrobasal complex. The thalamocortical connections of somatosensory cortices I and II in raccoon are compared with those in other animals and it is suggested that these two cortical areas may be involved in differential processing of tactile information.
利用辣根过氧化物酶技术，在浣熊身上研究了丘脑皮质传入到躯体感觉皮质I区（SI）和II区（SII）的情况。本研究的目的是确定投射到这些皮质区域的丘脑皮质传入纤维的起源细胞体是否位于丘脑腹后区的同一核团或不同核团。将辣根过氧化物酶注入SI或SII的亚区，在注射后12 - 72小时的存活期后，组织中的辣根过氧化物酶在过氧化氢存在的情况下与显色剂二盐酸联苯胺或四甲基联苯胺发生反应。结果表明，SI和SII接受来自丘脑腹后区不同核团中神经元的投射。向I区亚区注射后，在腹侧基底复合体中观察到逆行标记细胞体的拓扑分布。向II区亚区注射辣根过氧化物酶后，在腹后下核中观察到标记细胞体的拓扑分布。在腹侧基底复合体中未观察到标记细胞体。将浣熊躯体感觉皮质I和II的丘脑皮质连接与其他动物的进行了比较，并提出这两个皮质区域可能参与触觉信息的差异处理。
