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猫和浣熊脊髓注射后辣根过氧化物酶顺行运输在丘脑的分布及局部组织学结构

The distribution and topographical organization in the thalamus of anterogradely-transported horseradish peroxidase after spinal injections in cat and raccoon.

作者信息

Craig A D, Burton H

出版信息

Exp Brain Res. 1985;58(2):227-54. doi: 10.1007/BF00235306.

DOI:10.1007/BF00235306
PMID:3996495
Abstract

The distribution of anterogradely-transported horseradish peroxidase (HRP) was examined in the rostral mesencephalon and thalamus of cats and raccoons that had received injections of HRP in the cervical and/or lumbosacral enlargements of the spinal cord. Labeling was consistently observed in a large number of loci. All regions previously identified as targets of spinomesencephalic or spinothalamic fibers were included. Evidence of topographical organization was obtained in several regions. Adjacent fields of labeling were often separable on the basis of the distribution, appearance and topographical organization of the labeling. Subject to the methodological constraints imposed by the possibilities of transneuronal and/or collateral labeling, we conclude that a wide variety of loci in the thalamus receive direct spinal input. The organization of these projections suggests that each terminal region may be associated with different aspects of spinal cord function.

摘要

在猫和浣熊的延髓和丘脑中,研究了顺行运输的辣根过氧化物酶(HRP)的分布情况,这些动物在脊髓颈段和/或腰骶膨大处注射了HRP。在大量位点持续观察到标记。之前被确定为脊髓中脑或脊髓丘脑纤维靶点的所有区域都包括在内。在几个区域获得了拓扑组织的证据。相邻的标记区域通常可根据标记的分布、外观和拓扑组织进行区分。考虑到跨神经元和/或侧支标记可能性所带来的方法学限制,我们得出结论,丘脑中的多种位点接受直接的脊髓输入。这些投射的组织表明,每个终末区域可能与脊髓功能的不同方面相关。

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1
The distribution and topographical organization in the thalamus of anterogradely-transported horseradish peroxidase after spinal injections in cat and raccoon.猫和浣熊脊髓注射后辣根过氧化物酶顺行运输在丘脑的分布及局部组织学结构
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