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Vitamin D: two dihydroxylated metabolites are required for normal chicken egg hatchability.

作者信息

Henry H L, Norman A W

出版信息

Science. 1978 Sep 1;201(4358):835-7. doi: 10.1126/science.684411.

DOI:10.1126/science.684411
PMID:684411
Abstract

When hens are raised to sexual maturity from hatching with 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] as their sole source of cholecalciferol (vitamin D3), fertile eggs appear to develop normally but fail to hatch. When hens receive a combination of 1,25(OH)2D3 and 24R,25-dihydroxyvitamin D3 [24,25(OH)2D3], hatchability equivalent to that with hens given vitamin D3 is obtained. These results suggest a biological role for 24,25(OH)2D3 not previously recognized.

摘要

相似文献

1
Vitamin D: two dihydroxylated metabolites are required for normal chicken egg hatchability.
Science. 1978 Sep 1;201(4358):835-7. doi: 10.1126/science.684411.
2
Normal egg hatchability requires the simultaneous administration to the hen of 1 alpha,25-dihydroxycholecalciferol and 24R,25-dihydroxycholecalciferol.正常的孵化率要求同时给母鸡投喂1α,25-二羟基胆钙化醇和24R,25-二羟基胆钙化醇。
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Hydroxylation of carbon-24 of 25-hydroxycholecalciferol is not necessary for normal embryonic development in chickens.25-羟基胆钙化醇的C-24羟基化对于鸡的正常胚胎发育并非必需。
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Lack of response of bone mineralization of chicks fed egg yolks from hens on dietary 1,25 dihydroxycholecalciferol.
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9
Activity of ornithine decarboxylase and creatine kinase in soft and hard tissue of vitamin D-deficient chicks following parenteral application of 1,25-dihydroxyvitamin D3 or 24R,25-dihydroxyvitamin D3.在缺乏维生素D的雏鸡经肠胃外给予1,25 - 二羟基维生素D3或24R,25 - 二羟基维生素D3后，其软组织和硬组织中鸟氨酸脱羧酶及肌酸激酶的活性
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10
Stimulation of 24R,25-dihydroxyvitamin D3 synthesis by metabolites of vitamin D3.
Am J Physiol. 1983 Oct;245(4):E359-64. doi: 10.1152/ajpendo.1983.245.4.E359.

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