[Subcellular distribution of the Ca++-dependent protein regulator in the gray matter of the rat brain in normal conditions and on exposure to roentgen radiation].

It was shown that calmodulin is nonuniformly distributed in subcellular fractions of rat brain gray substance. The largest calmodulin content is found in the synaptosomal-mitochondrial fraction and the lowest, in the microsomal fraction. Different subcellular fractions of rat brain gray substance are characterized by diverse specific activities of calmodulin. Lethal X-radiation doses elicit substantial, oppositely directed, changes in the content and specific activity of calmodulin in different subcellular fractions of rat brain gray substance.