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[体内照射条件下淋巴细胞在体内的迁移。2. 器官中淋巴细胞微环境因素的紊乱]

[Lymphocyte migration in the body in conditions of internal irradiation. 2. Disorders of lymphocyte microenvironmental factors in organs].

作者信息

Anokhin Iu N, Norets T A, Iarilin A A

出版信息

Radiobiologiia. 1983 Mar-Apr;23(2):256-9.

PMID:6844566
Abstract

At later times after the injection of selenium-75-selenium methionine to CBA mice the inhibition of migration of intravenously injected normal 51Cr lymphocytes to the lymph nodes and liver lasted for a long time. On the contrary, no changes in the normal lymphocyte migration within the animal body were observed after total-body gamma-irradiation with the dose of 4 Gy. The data obtained are indicative of the radiation-induced disturbance of the microenvironment factors, which provide migration of lymphocytes within the body, during the long-term exposure to radiation emitted by the incorporated source.

摘要

给CBA小鼠注射硒-75-硒蛋氨酸后,在随后的时间里,静脉注射的正常51Cr淋巴细胞向淋巴结和肝脏的迁移抑制持续了很长时间。相反,用4 Gy剂量进行全身γ射线照射后,未观察到动物体内正常淋巴细胞迁移有变化。所获得的数据表明,在长期暴露于掺入源发出的辐射期间,辐射会引起体内淋巴细胞迁移所需微环境因素的紊乱。

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